Application
Western blot analysis in K562 cell line lysates (35ug/lane).Application
Western blot analysis of CTDSP1 using rabbit polyclonal p38 beta Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CTDSP1 gene (Lane 2).| Product Name | MAPK11 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | P38 beta is a member of the MAP kinase subfamily of Ser/Thr protein kinases. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is closely related to p38 MAP kinase, both of which can be activated by changes in osmolarity of the extracellular environment, proinflammatory cytokines and cellular stress. This protein preferentially phosphorylates transcription factor ATF2. It is activated by phosphorylation on threonine and tyrosine by MKK6, and inhibited by pyridinyl-imidazole related compounds. Highest levels of expression are found in the brain and heart, with additional expression in the placenta, lung, liver, skeletal muscle, kidney and pancreas.1) Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002). |
| Immunogen | This MAPK11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-161 amino acids from the Central region of human MAPK11. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000 | |
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | MAPK11 |
|---|---|
| Alternative Names | Mitogen-activated protein kinase 11 MAP kinase 11 MAPK 11 Mitogen-activated protein kinase p38 beta MAP kinase p38 beta p38b Stress-activated protein kinase 2b SAPK2b p38-2 MAPK11 PRKM11 SAPK2 SAPK2B |
| Molecular Weight(MW) | 41 kDa |
Application
Western blot analysis in K562 cell line lysates (35ug/lane).
Application
Western blot analysis of CTDSP1 using rabbit polyclonal p38 beta Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CTDSP1 gene (Lane 2).| Application Notes | For WB starting dilution is: 1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
