Application
Western blot analysis using MAPK11 monoclonal antibody against truncated MAPK11 - Trx recombinant protein and full - length MAPK11 (aa1 - 363) / pcDNA3.1 transfected CHO - K1 cell lysate.| Product Name | MAPK11 Antibody [4H6H6] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mitogen-activated protein kinase 11.The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. This kinase is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase.1) Mol Cell Biol. 2005 Dec;25(23):10454-64. |
| Immunogen | Purified truncated recombinant MAPK11 (aa251-363)-Trx fusion protein is expressed in E. Coli strain BL21 (DE3). |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | ELISAWB |
| Western Blot:1:500 - 1:2,000 ELISA:Propose dilution 1:10,000. Determining optimal working dilutions by titration test. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Symbol | MAPK11 |
|---|---|
| Alternative Names | P38B SAPK2 p38-2 PRKM11 SAPK2B p38Beta P38BETA2 |
| Entrez Gene | 5600 |
|---|---|
| Protein Accession | NP_002742.3 |
Application
Western blot analysis using MAPK11 monoclonal antibody against truncated MAPK11 - Trx recombinant protein and full - length MAPK11 (aa1 - 363) / pcDNA3.1 transfected CHO - K1 cell lysate.| Application Notes | Western Blot:1:500 - 1:2,000 ELISA:Propose dilution 1:10,000. Determining optimal working dilutions by titration test. |
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| Form | Liquid |
|---|---|
| Storage Instructions | MAPK11 monoclonal antibody can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Ascitic fluid containing 0.03% sodium azide. |
