Application
Western blot analysis of lysed extracts from Rat and Mouse brain tissue using MEK5 (phospho-Ser311/ Thr315).| Product Name | MEK5 (phospho Ser311 / Thr315) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appear to play a critical role in protecting cells from stress-induced apopotosis, neuronal survival and cardiac development and angiogenesis.1) English J. M., Vanderbilt C. A., Xu S., Marcus S., Cobb M. H. J. Biol. Chem. 270:28897-28902 (1995) |
| Immunogen | MEK5 (phospho-Ser311/ Thr315) antibody was raised against a peptide sequence around phosphorylation site of Serine 311 and threonine 315 (V-N-S (p) I-A-K-T (p) -Y-V) derived from Rat MEK5. |
| Modification | p-Ser311 / Thr315 |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | WB |
| Western Blot: 1:500~1:1000 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | Map2k5 |
|---|---|
| Alternative Names | Mek5 CDC2 CDC28A CDKN1 P34CDC2 Map2k5 |
| Molecular Weight(MW) | 46 kDa |
| Tissue Specificity | This antibody detects endogenous level of MEK5 only when phosphorylated at serine 311 or threonine 315. |
| Entrez Gene | 29568 |
|---|---|
| Protein Accession | NP_001029159.1 |
Application
Western blot analysis of lysed extracts from Rat and Mouse brain tissue using MEK5 (phospho-Ser311/ Thr315).| Application Notes | Western Blot: 1:500~1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
