MME, also known as Neprilysin or CALLA for common acute lymphocytic leukemia antigen, is a Metallopeptidase M13 type protease. MME functions as a peptidase and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. The protein is found on leukemic cells of pre-B phenotype and serves as a cell-surface marker in the diagnosis of human acute lymphocytic leukemia (ALL).
Immunogen
MME monoclonal antibody was raised against Ni-NTA purified recombinant human CD-10 expressed in E. Coli strain BL21 (DE3)
Key Feature
Clonality
Monoclonal
Isotype
IgG2b
Host Species
Mouse
Tested Applications
ELISAIHC
MME antibody can be used in ELISA starting at 1:10000 - 1:40000, Western Blot starting at 1:1000 - 1:4000, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 1:500 - 1:2000.:
Immunohistochemistry staining of MME in spleen tissue using MME monoclonal Antibody.
Application Notes
MME antibody can be used in ELISA starting at 1:10000 - 1:40000, Western Blot starting at 1:1000 - 1:4000, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 1:500 - 1:2000.:
Additional Information
Form
Liquid
Storage Instructions
Store MME antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles.