Application
Immunohistochemistry staining of NR4A1 in primary follicles tissue using NR4A1 Antibody.| Product Name | NR4A1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NR4A1, GFRP1, Early response protein NAK1, HMR, NGFIB, Orphan nuclear receptor TR3, Orphan receptor tr3, Steroid receptor TR3, TR3, NAK1, NGFI-B, NP10, Receptor NGFIB, Testicular receptor 3, TR3 orphan receptor, N10, NAK-1, NUR77, Orphan nuclear receptor H |
| Product description | Nak1, a NR4 Nerve Growth Factor-Like receptor, has been shown to affect the hypothalamic-pituitary axis, neuronal differentiation, neuroendocrine regulation of adrenocortical function, and T-cell apoptosis. Nak1 also is known as nuclear receptor Tr3 and is similar to mouse Nur77 and rat NGFI-B. It is encoded by one of the immediate early genes (IEG) in response to nerve growth factor and other serum growth factors. Nak1 can bind to DNA as a monomer, homodimer, or heterodimer (with retinoid X receptors). Nak1 has been shown to inhibit vascular lesion formation and could serve as a novel target in the treatment of vascular diseases. |
| Immunogen | NR4A1 antibody was raised against a peptide located near the internal domain of NR4A1 (Human). |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | IHC |
| NR4A1 antibody can be used in ELISA, Western Blot, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 10 μg/mL.: |
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| Species Reactivity | GibbonHorseHumanMonkeyOrangutan |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | NR4A1 |
|---|---|
| Alternative Names | NR4A1 GFRP1 Early response protein NAK1 HMR NGFIB Orphan nuclear receptor TR3 Orphan receptor tr3 Steroid receptor TR3 TR3 NAK1 NGFI-B NP10 Receptor NGFIB Testicular receptor 3 TR3 orphan receptor N10 NAK-1 NUR77 Orphan nuclear receptor H |
| Tissue Specificity | BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
Application
Immunohistochemistry staining of NR4A1 in primary follicles tissue using NR4A1 Antibody.| Application Notes | NR4A1 antibody can be used in ELISA, Western Blot, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 10 μg/mL.: |
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| Form | Liquid |
|---|---|
| Storage Instructions | NR4A1 antibody should be stored long term (months) at -80 ˚C and short term (days) at 4 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | PBS, 0.1% sodium azide. |
