Application
Immunohistochemistry staining of NTRK1 in adrenal tissue using NTRK1 Antibody.| Product Name | NTRK1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NTRK1, Oncogene TRK, TrkA/NGF receptor, Tropomyosin-related kinase A, TRK, TRK1, Tyrosine kinase receptor, Tyrosine kinase receptor A, gp140trk, MTC, p140-TrkA, Trk-A, TRKA |
| Product description | NTRK1 (trkA), a Trk/Ror type protein kinase, is a high-affinity receptor for the nerve growth factor NGF. NTRK1 has been shown to regulate neural development and maintenance of neural network. Mutation in NTRK1 gene is responsible for congenital insensitivity to pain with anhidrosis (CIPA), an autosomal recessive hereditary disorder characterized by recurrent episodic fever, anhidrosis (inability to sweat), absence of reaction to noxious stimuli, self-mutilating behavior, and mental retardation. Rearrangements and fusion of NTRK1 gene to other genes have been implicated in colon and papillary thyroid cancers. Two protein isoforms have been identified. |
| Immunogen | NTRK1 antibody was raised against a synthetic peptide surrounding amino acid 494 of NTRK1 (Human). |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | IHCIPWB |
| NTRK1 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 10 μg/mL.: |
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| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | NTRK1 |
|---|---|
| Alternative Names | NTRK1 Oncogene TRK TrkA/NGF receptor Tropomyosin-related kinase A TRK TRK1 Tyrosine kinase receptor Tyrosine kinase receptor A gp140trk MTC p140-TrkA Trk-A TRKA |
| Tissue Specificity | Does not cross-react with TrkB or TrkC. |
Application
Immunohistochemistry staining of NTRK1 in adrenal tissue using NTRK1 Antibody.| Application Notes | NTRK1 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 10 μg/mL.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store NTRK1 antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | PBS, pH 7.2, 30% glycerol, 0.5% BSA, 0.01% Thimerosal. |
Data sheet for OM286670