Nuclear pore complex protein Nup50, 50 kDa nucleoporin, Nuclear pore-associated protein 60 kDa-like, Nucleoporin Nup50, NUP50, NPAP60L
Product description
The nuclear pore complex is a massive structure that
extends across the nuclear envelope, forming a gateway that
regulates the flow of macromolecules between the nucleus and the
cytoplasm. Nucleoporins are the main components of the nuclear pore
complex in eukaryotic cells. The protein encoded by this gene is a
member of the FG-repeat containing nucleoporins that functions as a
soluble cofactor in importin-alpha:beta-mediated nuclear protein
import. Pseudogenes of this gene are found on chromosomes 5, 6, and
14. Two transcript variants encoding different isoforms have been
found for this gene.1) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Immunogen
This NUP50 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 224-252 amino acids from the Central region of human NUP50.
Western blot analysis in WiDr cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.