Application
Western blot analysis of RUNX1 in Raji cell lysate with RUNX1 antibody at (A) 1 and (B) 2 μg/mL.| Product Name | RUNX1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RUNX1 Antibody: AML1, CBFA2, EVI-1, AMLCR1, PEBP2aB, AML1-EVI-1, AML1, Runt-related transcription factor 1, Acute myeloid leukemia 1 protein, CBF-alpha-2 |
| Product description | RUNX1 Antibody: RUNX1 is one of three mammalian RUNX genes that control multiple aspects of embryonic development and are responsible for the pathogenesis of many human diseases. RUNX1 plays major roles in the development of nociceptive sensory neurons in addition to hematopoietic stem cells (HSC) with the exception of the erythroid lineage. During development, Notch signals mediate RUNX1 induction with SCL/GATA/Ets factors, and Wnt signals potentially cooperate with RUNX1 to facilitate adult HSC expansion via cooperative induction of cyclin D, cdk4, and other cell cycle regulators. In turn, RUNX1 regulates cell cycle transitions dependent on functional/physical interactions with other proteins such as HDAC1 and -3, mSin3A, p300, SMAD proteins, and LEF/TCF.1) Lund AH and van Lohuizen M. RUNX: a trilogy of cancer genes. Cancer Cell2002; 1:213-5. |
| Immunogen | RUNX1 antibody was raised against a 16 amino acid synthetic peptide from near the center of human RUNX1. The immunogen is located within amino acids 160 - 210 of RUNX1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| RUNX1 antibody can be used for detection of RUNX1 by Western blot at 1 - 2 μg/mL.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | RUNX1 |
|---|---|
| Alternative Names | RUNX1 Antibody: AML1 CBFA2 EVI-1 AMLCR1 PEBP2aB AML1-EVI-1 AML1 Runt-related transcription factor 1 Acute myeloid leukemia 1 protein CBF-alpha-2 |
Application
Western blot analysis of RUNX1 in Raji cell lysate with RUNX1 antibody at (A) 1 and (B) 2 μg/mL.| Positive Control | 1) Cat. No. 1207 - Raji Cell Lysate |
|---|---|
| Application Notes | RUNX1 antibody can be used for detection of RUNX1 by Western blot at 1 - 2 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | RUNX1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | RUNX1 Antibody is supplied in PBS containing 0.02% sodium azide. |
