Application
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using SEK1/MKK4 (Ab-261).Application
Immunofluorescence staining of methanol-fixed HeLa cells using SEK1/MKK4 (Ab-261).| Product Name | SEK1 / MKK4 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Dual specificity kinase that activates the JUN kinases MAPK8 (JNK1) and MAPK9 (JNK2) as well as MAPK14 (p38) but not MAPK1 (ERK2) or MAPK3 (ERK1).1) Wang W, et al. (2002) Mol Cell Biol; 22 (10): 3389-403. Leung IW, et al. (2001) J Biol Chem; 276 (3): 1961-7. |
| Immunogen | SEK1/MKK4 (Ab-261) antibody was raised against a peptide sequence around aa.259~263 (A-K-T-R-D) derived from Human SEK1/MKK4. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | IFIHC |
| Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | MAP2K4 |
|---|---|
| Alternative Names | JNKK MEK4 MKK4 SEK1 SKK1 JNKK1 SERK1 MAPKK4 PRKMK4 SAPKK1 SAPKK-1 C9orf88 JNKK MAP2K4 MAPK/ERK kinase 4 MAPKK 4 |
| Molecular Weight(MW) | 44 kDa |
| Tissue Specificity | This antibody detects endogenous level of total SEK1/MKK4 protein. |
| Entrez Gene | 6416 |
|---|---|
| Protein Accession | NP_003001.1 |
Application
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using SEK1/MKK4 (Ab-261).
Application
Immunofluorescence staining of methanol-fixed HeLa cells using SEK1/MKK4 (Ab-261).| Application Notes | Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
