Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
TRPM8 is a receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. It is activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH and involved in menthol sensation. It is permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium.1) Tsavaler L.,Cancer Res. 61:3760-3769(2001).
Immunogen
This TRPM8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 926-956 amino acids from the C-terminal region of human TRPM8.
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50
Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
Application Notes
For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.