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Anti-H2AFX antibody-HRP

Catalog Number:OM642372-HRP
Human;Mouse;Rat
WB;IHC
OM642372-HRP
Discount Price
OM642372-HRP-100ul
1~2 Week
100ul
1~2 Week
Product Profile
Product Name Anti-H2AFX antibody-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol H2AX
Gene Synonyms H2A.X
H2A/X
H2AFX
Gene Full Name H2A.X variant histone
Gene Summary Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.
Molecular Weight(MW) 15 kDa(observed:20kDa)
Cellular Localization Chromosome, Nucleosome core, Nucleus
Database Links
SwissProt ID P16104
Application

IHC

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using H2AFX antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human rectal cancer tissues using H2AFX antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissues using H2AFX antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using H2AFX antibody with DAB staining.

WB

Western blot analysis using H2AFX antibody against Rat kidney tissue(1),Rat liver tissue(2).
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
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