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Anti -Slow Skeletal Myosin Heavy chain Rabbit pAb

Catalog Number:OM642750
Human;Mouse;Rat
ICC/IF;IHC;WB
OM642750
Discount Price
OM642750-100ul
1~2 Week
100ul
1~2 Week
Product Profile
Product Name Anti -Slow Skeletal Myosin Heavy chain Rabbit pAb
Antibody Type Primary Antibodies
Immunogen KLH conjugated Synthetic peptide corresponding to Human MYH7
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Alligator
Tested Applications ICC/IFIHCWB
WB:1: 300-1: 600
IF:1: 500-1: 1000
Species Reactivity HumanMouseRat
Purification Affinity purified
Target Information
Gene Symbol MYH7
Gene Synonyms CMH1
MPD1
SPMD
SPMM
CMD1S
MYHCB
CMYP7A
CMYP7B
Gene Full Name myosin heavy chain 7
Gene Summary Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing distal myopathy. [provided by RefSeq, May 2022]
Molecular Weight(MW) 223KD
Cellular Localization Cytoplasm
Application

WB

Western blot analysis of MYH7 at dilution of 1: 600

IHC

Immunohistochemistry analysis of paraffin-embedded rat muscle using MYH7 at dilution of 1: 1000

IF

Immunofluorescent analysis of paraformaldehyde-fixed rat skeletal muscle using MYH1 (red) and MYH7 (green) at dilution of 1: 1000
Application Notes WB:1: 300-1: 600
IF:1: 500-1: 1000
Additional Information
Form Liquid
Storage Instructions Store at -20℃ for one year. Avoid repeated freeze/thaw cycle.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/mL BSA and 50%.
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