Application
Western Blot at 1:1000 dilution + human skeletal muscle lysate Lysates/proteins at 20 ug per lane.Application
Western blot analysis in mouse spleen tissue lysates (35ug/lane).| Product Name | MYH7 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy.1) Millat, G., et al. Clin. Chim. Acta 411 (23-24), 1983-1991 (2010) : |
| Immunogen | This MYH7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 185-211 amino acids from the N-terminal region of human MYH7. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000 | |
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | MYH7 |
|---|---|
| Alternative Names | Myosin-7 Myosin heavy chain 7 Myosin heavy chain slow isoform MyHC-slow Myosin heavy chain cardiac muscle beta isoform MyHC-beta MYH7 MYHCB |
| Molecular Weight(MW) | 223 kDa |
Application
Western Blot at 1:1000 dilution + human skeletal muscle lysate Lysates/proteins at 20 ug per lane.
Application
Western blot analysis in mouse spleen tissue lysates (35ug/lane).| Application Notes | For WB starting dilution is: 1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
