WB
Western blot analysis of Mfn2 expression in whole cell lysate of Hep G2 (A), NIH/3T3 (B), K-562 (C), A-673 (D), and c4 (E).WB
Western blot analysis of Mfn2 expression in Hep G2 (A), A-10 (B), HeLa (C), and K-562 (D) whole cell lysate and human heart tissue extract (E)WB
Western blot analysis of Mfn2 expression in whole cell lysate of non transfected (A) and human Mfn2 transfected (B) cells.| Product Name | Mouse Monoclonal antibody to Mfn2/Mitofusin 2 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | raised against amino acids 461-528 mapping within a cytoplasmic domain of Mfn2 of human origin |
| Clonality | monoclonal |
|---|---|
| Isotype | IgG1, k |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:1:100-1:1000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 0.2mg/ml |
| Purification | Affinity purified |
| Gene Symbol | MFN2 |
|---|---|
| Gene Synonyms | HSG MSL MARF CMT2A CPRP1 CMT2A2 HMSN6A CMT2A2A CMT2A2B |
| Gene Full Name | mitofusin 2 |
| Gene Summary | This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008] |
| Molecular Weight(MW) | 86 kDa |
WB
Western blot analysis of Mfn2 expression in whole cell lysate of Hep G2 (A), NIH/3T3 (B), K-562 (C), A-673 (D), and c4 (E).
WB
Western blot analysis of Mfn2 expression in Hep G2 (A), A-10 (B), HeLa (C), and K-562 (D) whole cell lysate and human heart tissue extract (E)
WB
Western blot analysis of Mfn2 expression in whole cell lysate of non transfected (A) and human Mfn2 transfected (B) cells.| Application Notes | WB:1:100-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4° C, **DO NOT FREEZE**. Stable for one year from the date of shipment. Non-hazardous. No MSDS required. |
| Storage Buffer | Each vial contains 200 µg IgG1 kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin. |
