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Mouse Monoclonal antibody to Gephyrin

Catalog Number:OM645492
OM645492
Discount Price
OM645492-100ul
100ul
Product Profile
Product Name Mouse Monoclonal antibody to Gephyrin
Antibody Type Primary Antibodies
Immunogen y raised against amino acids 569-726 of Gephyrin of rat origin
Key Feature
Clonality Monoclonal
Isotype IgG1
Host Species Mouse
Tested Applications IHCWB
WB:1:100-1:1000
IHC:1:50-1:500
Species Reactivity HumanMouseRat
Concentration 0.1mg/ml
Purification Affinity purified
Target Information
Gene Symbol GPHN
Gene Synonyms GPH
GEPH
HKPX1
GPHRYN
MOCODC
Gene Full Name gephyrin
Gene Summary This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described; however, the full-length nature of all transcript variants is not currently known. [provided by RefSeq, Jul 2008]
Molecular Weight(MW) 93 kDa
Application

WB

Western blot analysis of Gephyrin expression in rat brain tissue extracts.

IHC

Immunoperoxidase staining of rat cerebellar tissue fixed in formalin and embedded in paraffin reveals cytoplasmic staining.
Application Notes WB:1:100-1:1000
IHC:1:50-1:500
Additional Information
Form Liquid
Storage Instructions Store at 4° C, **DO NOT FREEZE**. Stable for one year from the date of shipment. Non-hazardous. No MSDS required.
Storage Buffer Each vial contains 50 µg IgG1 light chain in 0.5 ml of PBS with < 0.1% sodium azide and 0.1% gelatin.
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