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Mouse Monoclonal antibody to NOR-1

Catalog Number:OM645612
OM645612
Discount Price
OM645612-100ul
100ul
Product Profile
Product Name Mouse Monoclonal antibody to NOR-1
Antibody Type Primary Antibodies
Immunogen amino acids 222-259 within an internal region of NOR-1 of human origin.
Key Feature
Clonality Monoclonal
Isotype IgG1, k
Host Species Mouse
Tested Applications ICC/IFWB
WB:1:100-1:1000
ICC/IF:1:50-1:500
Species Reactivity HumanMousePorcineRat
Concentration 0.1mg/ml
Purification Affinity purified
Target Information
Gene Symbol NR4A3
Gene Synonyms CHN
CSMF
NOR1
MINOR
Gene Full Name nuclear receptor subfamily 4 group A member 3
Gene Summary This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcriptional activator. The protein can efficiently bind the NGFI-B Response Element (NBRE). Three different versions of extraskeletal myxoid chondrosarcomas (EMCs) are the result of reciprocal translocations between this gene and other genes. The translocation breakpoints are associated with Nuclear Receptor Subfamily 4, Group A, Member 3 (on chromosome 9) and either Ewing Sarcome Breakpoint Region 1 (on chromosome 22), RNA Polymerase II, TATA Box-Binding Protein-Associated Factor, 68-KD (on chromosome 17), or Transcription factor 12 (on chromosome 15). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
Molecular Weight(MW) 68 kDa
Cellular Localization Nucleus
Application

WB

Western blot analysis of NOR-1 expression in non-transfected:(A) and mouse NOR-1 transfected: (B) 293 whole cell lysates.

ICC/IF

Immunofluorescence staining of formalin-fixed A-431 cells showing nuclear localization.
Application Notes WB:1:100-1:1000
ICC/IF:1:50-1:500
Additional Information
Form Liquid
Storage Instructions Store at 4° C, **DO NOT FREEZE**. Stable for one year from the date of shipment. Non-hazardous. No MSDS required.
Storage Buffer Each vial contains 200 µg IgG1 kappa light chain in 1.0 ml of PBS with < 0.1%sodium azide and 0.1% gelatin.
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