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Endothelin A Receptor Rabbit mAb
Catalog Number:OM645846
OM645846
Discount Price
OM645846-100ul
100ul
OM645846-50ul
50ul
Product Profile
Product Name Endothelin A Receptor Rabbit mAb
Antibody Type Primary Antibodies
Immunogen The specific immunogen used to produce this antibody is proprietary information.
Key Feature
Clonality Monoclonal
Isotype IgG,K
Host Species Rabbit
Tested Applications ICC/IFIHCWB
WB: 1:500-1:2000
IHC:1:200-1:1000
ICC/IF:1:200-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol EDNRA
Gene Synonyms ETA
ET-A
ETAR
ETRA
MFDA
ETA-R
hET-AR
Gene Full Name endothelin receptor type A
Gene Summary This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Alternative Names EDNRA
ETA
ETRA
Endothelin-1 receptor
Endothelin A receptor
ET-A
ETA-R
hET-AR
Molecular Weight(MW) 49 kDa(Observed band size: 65 kDa)
Cellular Localization Cell membrane; Multi-pass membrane protein.
Application

WB

Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-Endothelin A Receptor antibody. The HRP-conjugated Goat anti-Rabbit IgG (H + L) antibody was used to detect the antibody.

IHC

Human placenta was stained with anti-Endothelin A Receptor (PT1210R) Rabbit antibody.

ICC/IF

Immunofluorescence analysis of LOVO cells, using EDNRA Antibody. The picture on the right is blocked with the synthesized peptide.
Application Notes WB: 1:500-1:2000
IHC:1:200-1:1000
ICC/IF:1:200-1:1000
Additional Information
Form Liquid
Storage Instructions -15°C to -25°C/1 year(Do not lower than -25°C)
Storage Buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
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