WB
MNDA Antibody: Western blot analysis of MNDA expression in THP-1 whole cell lysates.WB
MNDA Antibody: Western blot analysis of MNDA expression in whole cell lysates of untransfected 293T:(A), human MNDA-transfected 293T: (B), and (C).IHC
MNDA Antibody (C-3): Immunoperoxidase staining of formalin-fixed, paraffin-embedded human spleen tissue shows nuclear staining in white pulp and red pulp cells. Note intense nuclear staining of lymphocyte subsets within the red pulp.| Product Name | Mouse Monoclonal antibody to MNDA |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | amino acids 372-407 of MNDA of human origin. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1, k |
| Host Species | Mouse |
| Tested Applications | IHCWB |
| WB:1:100-1:1000 IHC:1:50-1:500 |
|
| Species Reactivity | Human |
| Concentration | 0.1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | MNDA |
|---|---|
| Gene Synonyms | PYHIN3 |
| Gene Full Name | myeloid cell nuclear differentiation antigen |
| Gene Summary | The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2,200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons. [provided by RefSeq, Jul 2008] |
| Molecular Weight(MW) | 55 kDa |
| Cellular Localization | Cytoplasm,Nucleus |
WB
MNDA Antibody: Western blot analysis of MNDA expression in THP-1 whole cell lysates.
WB
MNDA Antibody: Western blot analysis of MNDA expression in whole cell lysates of untransfected 293T:(A), human MNDA-transfected 293T: (B), and (C).
IHC
MNDA Antibody (C-3): Immunoperoxidase staining of formalin-fixed, paraffin-embedded human spleen tissue shows nuclear staining in white pulp and red pulp cells. Note intense nuclear staining of lymphocyte subsets within the red pulp.| Application Notes | WB:1:100-1:1000 IHC:1:50-1:500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4° C, **DO NOT FREEZE**. Stable for one year from the date of shipment. Non-hazardous. No MSDS required. |
| Storage Buffer | Each vial contains 200 µg IgG1 kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin. |
