IHC
Immunohistochemical analysis of paraffin-embedded Human Skeletal Muscle Tissue using NBR1 Mouse mAb diluted at 1:200.| Product Name | Mouse anti-NBR1 Monoclonal antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Recombinant Protein |
| Clonality | Monoclonal |
|---|---|
| Host Species | Mouse |
| Tested Applications | IHC |
| IHC:1:50-1:200 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | NBR1 |
|---|---|
| Gene Synonyms | IAI3B M17S2 MIG19 1A1-3B |
| Gene Full Name | NBR1 autophagy cargo receptor |
| Gene Summary | The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014] |
| Alternative Names | 1A1 3B antibody 1A13B antibody B box protein antibody Cell migration-inducing gene 19 protein antibody KIAA0049 antibody M17S2 antibody Membrane component chromosome 17 surface marker 2 antibody Membrane component chromosome 17 surface marker 2 (ovarian carcinoma antigen CA125) antibody MIG 19 antibody MIG19 antibody Migration inducing protein 19 antibody NBR 1 antibody Nbr1 antibody NBR1 autophagy cargo receptor antibody NBR1_HUMAN antibody Neighbor of BRCA1 gene 1 antibody Neighbor of BRCA1 gene 1 protein antibody Next to BRCA1 gene 1 protein antibody Ovarian carcinoma antigen CA125 antibody Protein 1A1-3B antibody |
| Cellular Localization | Cytoplasm. Cytoplasmic vesicle, autophagosome. Lysosome. Cytoplasm, myofibril, sarcomere, M line. |
IHC
Immunohistochemical analysis of paraffin-embedded Human Skeletal Muscle Tissue using NBR1 Mouse mAb diluted at 1:200.| Application Notes | IHC:1:50-1:200 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
