WB
ADAR1 HRP: Direct western blot analysis of ADAR1 expression in Ramos (A), HeLa (B) and K-562 (C) nuclear extracts and AN3 CA (D), NTERA-2 cl.D1 (E) and Ramos (F) whole cell lysates.ICC/IF
ADAR1 : Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear localization.IHC
ADAR1 antibody: Immunoperoxidase staining of formalin‑fixed, paraffin‑embedded human nasopharyngeal tissue shows nuclear staining in respiratory epithelial cells.| Product Name | Mouse Monoclonal antibody to ADAR1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | raised against amino acids 1051-1226 mapping at the C-terminus of ADAR1 of human origin. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | ICC/IFIHCWB |
| WB:1:100-1:1000 IHC:1:50-1:500 ICC/IF:1:50-1:50 |
|
| Species Reactivity | Human |
| Concentration | 0.1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ADAR |
|---|---|
| Gene Synonyms | DSH AGS6 G1P1 IFI4 P136 ADAR1 DRADA DSRAD IFI-4 K88DSRBP |
| Gene Full Name | adenosine deaminase RNA specific |
| Gene Summary | This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010] |
| Molecular Weight(MW) | 150 kDa |
| Cellular Localization | Cytoplasm,Nucleus. |
WB
ADAR1 HRP: Direct western blot analysis of ADAR1 expression in Ramos (A), HeLa (B) and K-562 (C) nuclear extracts and AN3 CA (D), NTERA-2 cl.D1 (E) and Ramos (F) whole cell lysates.
ICC/IF
ADAR1 : Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear localization.
IHC
ADAR1 antibody: Immunoperoxidase staining of formalin‑fixed, paraffin‑embedded human nasopharyngeal tissue shows nuclear staining in respiratory epithelial cells.| Application Notes | WB:1:100-1:1000 IHC:1:50-1:500 ICC/IF:1:50-1:50 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4° C, **DO NOT FREEZE**. Stable for one year from the date of shipment. Non-hazardous. No MSDS required. |
| Storage Buffer | Each vial contains 200 µg IgG1 lambda light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin. |
