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Osteocalcin Rabbit mAb

Catalog Number:OM647324
OM647324
Discount Price
OM647324-100ul
100ul
OM647324-50ul
50ul
Product Profile
Product Name Osteocalcin Rabbit mAb
Antibody Type Primary Antibodies
Immunogen The specific immunogen used to produce this antibody is proprietary information.
Key Feature
Clonality Monoclonal
Isotype IgG,K
Host Species Rabbit
Tested Applications IHCWB
WB:1:2000-1:10000
IHC:1:100-1:500
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol BGLAP
Gene Synonyms OC
BGP
OCN
Gene Full Name bone gamma-carboxyglutamate protein
Gene Summary This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product. [provided by RefSeq, Jun 2015]
Molecular Weight(MW) 11 kDa(Observed band size: 22 kDa)
Cellular Localization Secreted.
Application

WB

Various whole cell lysates were separated by 4-8% SDS-PAGE, and the membrane was blotted with anti-Osteocalcin antibody. The HRP-conjugated Goat anti-Rabbit IgG (H + L) antibody was used to detect the antibody.

IHC

Mouse liver was stained with anti-Osteocalcin rabbit antibody.

IHC

Human hepatocellular carcinoma was stained with anti-Osteocalcin rabbit antibody.
Application Notes WB:1:2000-1:10000
IHC:1:100-1:500
Additional Information
Form Liquid
Storage Instructions -15°C to -25°C/1 year (Do not lower than -25°C).
Storage Buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA.
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