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Monoclonal Antibody to Osteocalcin (OC)

Catalog Number:OM646555
OM646555
Discount Price
OM646555-100ul
100ul
Product Profile
Product Name Monoclonal Antibody to Osteocalcin (OC)
Antibody Type Primary Antibodies
Immunogen Recombinant Osteocalcin (Ala21~Pro99) expressed in E.coli.
Key Feature
Clonality Monoclonal
Isotype IgG1, k
Host Species Mouse
Tested Applications IHCWB
IHC:5-30µg/mL
WB:1:200-1:2000
Species Reactivity Human
Concentration 1mg/ml
Purification Protein A/G
Target Information
Gene Symbol BGLAP
Gene Synonyms OC
BGP
OCN
Gene Full Name bone gamma-carboxyglutamate protein
Gene Summary This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product. [provided by RefSeq, Jun 2015]
Alternative Names BGLAP
OT
BGP
Bone Gla Protein
Bone Gamma-Carboxyglutamate Protein
Gamma-carboxyglutamic acid-containing protein
Application

IHC

DAB staining on IHC-P; Samples: Human Skeletal muscle Tissue; Primary Ab: 30µg/ml Mouse Anti Human OC Antibody Second Ab: 2µg/mL HRP-Linked Caprine Anti Mouse IgG Polyclonal Antibody.

WB

Figure. Western Blot; Sample: Recombinant OC, Human.
Application Notes IHC:5-30µg/mL
WB:1:200-1:2000
Additional Information
Form Liquid
Storage Instructions Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 24 months.
Storage Buffer Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300,50% glycerol.
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