DAB staining on IHC-P; Samples:
Human Skeletal muscle Tissue;
Primary Ab: 30µg/ml Mouse Anti
Human OC Antibody Second Ab:
2µg/mL HRP-Linked Caprine Anti
Mouse IgG Polyclonal Antibody.
WB
Figure. Western Blot; Sample: Recombinant OC, Human.
Recombinant Osteocalcin (Ala21~Pro99) expressed in E.coli.
Key Feature
Clonality
Monoclonal
Isotype
IgG1, k
Host Species
Mouse
Tested Applications
IHCWB
IHC:5-30µg/mL WB:1:200-1:2000
Species Reactivity
Human
Concentration
1mg/ml
Purification
Protein A/G
Target Information
Gene Symbol
BGLAP
Gene Synonyms
OC BGP OCN
Gene Full Name
bone gamma-carboxyglutamate protein
Gene Summary
This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product. [provided by RefSeq, Jun 2015]
Alternative Names
BGLAP OT BGP Bone Gla Protein Bone Gamma-Carboxyglutamate Protein Gamma-carboxyglutamic acid-containing protein
Application
IHC
DAB staining on IHC-P; Samples:
Human Skeletal muscle Tissue;
Primary Ab: 30µg/ml Mouse Anti
Human OC Antibody Second Ab:
2µg/mL HRP-Linked Caprine Anti
Mouse IgG Polyclonal Antibody.
WB
Figure. Western Blot; Sample: Recombinant OC, Human.
Application Notes
IHC:5-30µg/mL WB:1:200-1:2000
Additional Information
Form
Liquid
Storage Instructions
Avoid repeated freeze/thaw cycles.
Store at 4ºC for frequent use.
Aliquot and store at -20ºC for 24 months.
Storage Buffer
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300,50% glycerol.