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Mouse Monoclonal antibody to Tropomyosin

Catalog Number:OM647733
OM647733
Discount Price
OM647733-100ul
100ul
Product Profile
Product Name Mouse Monoclonal antibody to Tropomyosin
Antibody Type Primary Antibodies
Immunogen amino acids 223-259 near the C-terminus of Tropomyosin b of human origin.
Key Feature
Clonality Monoclonal
Isotype IgG1, k
Host Species Mouse
Tested Applications IHCWB
WB:1:100-1:1000
IHC:1:50-1:500
Species Reactivity HumanMouseRat
Concentration 0.1mg/ml
Purification Affinity purified
Target Information
Gene Symbol TPM3
Gene Synonyms TM3
TM5
TRK
CFTD
NEM1
TM-5
TM30
CAPM1
CMYO4A
CMYO4B
CMYP4A
CMYP4B
TM30nm
TPM3nu
TPMsk3
hscp30
HEL-189
HEL-S-82p
OK/SW-cl.5
Gene Full Name tropomyosin 3
Gene Summary This gene encodes a member of the tropomyosin family of actin-binding proteins. Tropomyosins are dimers of coiled-coil proteins that provide stability to actin filaments and regulate access of other actin-binding proteins. Mutations in this gene result in autosomal dominant nemaline myopathy and other muscle disorders. This locus is involved in translocations with other loci, including anaplastic lymphoma receptor tyrosine kinase (ALK) and neurotrophic tyrosine kinase receptor type 1 (NTRK1), which result in the formation of fusion proteins that act as oncogenes. There are numerous pseudogenes for this gene on different chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
Molecular Weight(MW) 33 kDa,33 kDa,33 kDa,29 kDa(Observed band size: 31-47 kDa)
Cellular Localization Cytoplasm,Cytoskeleton.
Database Links
Application

WB

Tropomyosin Antibody : Tropomyosin Antibody. Western blot analysis of Tropomyosin expression in HeLa (A) and RAW 264.7 (B) whole cell lysates.

IHC

Tropomyosin Antibody : Tropomyosin Antibody. Immunoperoxidase staining of formalin fixed, paraffin-embedded human smooth muscle tissue showing cytoplasmic staining of smooth muscle cells.
Application Notes WB:1:100-1:1000
IHC:1:50-1:500
Additional Information
Form Liquid
Storage Instructions Store at 4° C, **DO NOT FREEZE**. Stable for one year from the date of shipment. Non-hazardous. No MSDS required.
Storage Buffer Each vial contains 200 µg IgG1 kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin.
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