ELISA
Coat the plate with immunizing antigen.Blue line： Immune serum; Orange line: Pre-immune serum.| Product Name | Anti-HEXA antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISA |
| ELISA:1:1000-1:10000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | HEXA |
|---|---|
| Gene Synonyms | Hex-1 TSD |
| Gene Full Name | hexosaminidase subunit alpha |
| Gene Summary | This gene encodes a member of the glycosyl hydrolase 20 family of proteins. The encoded preproprotein is proteolytically processed to generate the alpha subunit of the lysosomal enzyme beta-hexosaminidase. This enzyme, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene lead to an accumulation of GM2 ganglioside in neurons, the underlying cause of neurodegenerative disorders termed the GM2 gangliosidoses, including Tay-Sachs disease (GM2-gangliosidosis type I). Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016] |
| Alternative Names | beta-hexosaminidase beta-N-acetylhexosaminidase subunit alpha EC 3.2.1 EC 3.2.1.52 HEXA hexosaminidase A hexosaminidase A (alpha polypeptide) hexosaminidase A (alpha polypeptide) isoform HEXA_1 hexosaminidase A (alpha polypeptide) isoform HEXA_2 hexosaminidase A (alpha polypeptide) isoform HEXA_3 hexosaminidase A (alpha polypeptide) isoform HEXA_4 hexosaminidase A (alpha polypeptide) isoform HEXA_5 hexosaminidase subunit A Hexose aminidase A (alpha polypeptide) MGC99608 N-acetyl-alpha-glucosaminidase prepro-polypeptide N-acetyl-beta-glucosaminidase subunit alpha Unknown |
| Molecular Weight(MW) | 60kDa |
| Source | Rabbit |
| Cellular Localization | Lysosome |
| SwissProt ID | P06865 |
|---|
ELISA
Coat the plate with immunizing antigen.Blue line： Immune serum; Orange line: Pre-immune serum.| Application Notes | ELISA:1:1000-1:10000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300. |
