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Anti-NXF1 antibody

Catalog Number:OM663555
OM663555
Discount Price
OM663555-100ul
100ul
OM663555-50ul
50ul
OM663555-20ul
20ul
Product Profile
Product Name Anti-NXF1 antibody
Antibody Type Primary Antibodies
Immunogen Polypeptide
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ELISA
ELISA:1:1000-1:10000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol NXF1
Gene Synonyms MEX67
Mex67h
Mvb1
TAP
Gene Full Name nuclear RNA export factor 1
Gene Summary This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Alternative Names CTE RNA export factor
Mex 67 homolog
modifier of vibrator 1
mRNA export factor TAP
nuclear RNA export factor 1 homolog
TAP
tip associated protein
tip associating protein
tip-associated protein
tip-associating protein
Vdp
Molecular Weight(MW) 70kDa
Source Rabbit
Cellular Localization Nucleus;Nucleus, nucleoplasm;Nucleus speckle;Nucleus, nuclear pore complex;Nucleus envelope;Cytoplasm;Cytoplasm, Stress granule
Database Links
SwissProt ID Q9UBU9
Application

ELISA

Coat the plate with immunizing antigen.Blue line: Immune serum; Orange line: Pre-immune serum.
Application Notes ELISA:1:1000-1:10000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% PC300.
validation
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