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Anti-Phospho-Integrin beta3(Tyr785) Antibody

Catalog Number:OM681527
OM681527
Discount Price
OM681527-100ul
100ul
Product Profile
Product Name Anti-Phospho-Integrin beta3(Tyr785) Antibody
Antibody Type Primary Antibodies
Immunogen Synthetic peptide conjugated with KLH.
Modification p-Tyr785
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ELISA
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol Itgb3
Gene Synonyms CD61
GP3A
INGRB3
Gene Full Name integrin beta 3
Gene Summary Enables integrin binding activity and protein kinase C binding activity. Involved in several processes, including integrin-mediated signaling pathway; positive regulation of T cell migration; and positive regulation of osteoblast proliferation. Acts upstream of or within several processes, including blood coagulation; positive regulation of cell-substrate adhesion; and regulation of cell migration. Located in several cellular components, including apical plasma membrane; external side of plasma membrane; and focal adhesion. Part of alpha9-beta1 integrin-ADAM8 complex and alphav-beta3 integrin-PKCalpha complex. Is active in glutamatergic synapse and synaptic membrane. Is expressed in several structures, including bone; brain; early conceptus; genitourinary system; and gut. Used to study Glanzmann's thrombasthenia and platelet-type bleeding disorder 16. Human ortholog(s) of this gene implicated in several diseases, including autoimmune thrombocytopenic purpura; blood platelet disease (multiple); end stage renal disease; myocardial infarction; and non-arteritic anterior ischemic optic neuropathy. Orthologous to human ITGB3 (integrin subunit beta 3).
Alternative Names BDPLT16 antibody
BDPLT2 antibody
CD 61 antibody
CD61 antibody
CD61 antigen antibody
GP3A antibody
GPIIIa antibody
GT antibody
HPA 1 antibody
HPA 4 antibody
Integrin beta 3 (platelet glycoprotein IIIa antigen CD61) antibody
Integrin beta chain beta 3 antibody
Integrin beta-3 antibody
ITB3_HUMAN antibody
ITG B3 antibody
ITGB 3 antibody
ITGB3 antibody
NAIT antibody
platelet fibrinogen receptor antibody
Platelet fibrinogen receptor beta subunit antibody
Platelet fibrinogen receptor
beta subunit antibody
Platelet glycoprotein IIIa antibody
Platelet glycoprotein IIIa precursor antibody
Platelet membrane glycoprotein IIIa antibody
PTP antibody
Molecular Weight(MW) 87 kDa
Cellular Localization Cell membrane, Cell projection, lamellipodium membrane, Cell junction, focal adhesion, Postsynaptic cell membrane, Synapse.
Database Links
SwissProt ID P05106
Application

ELISA

Coat the plate with 100ng immunizing antigen. The phospho-specific antibody,pbs only can specifically recognize phosphorylated peptide and enable quantitative detection over a wide dynamic range. Non-phosphorylated peptide shows no cross-reactivity, and the background signal remains low, indicating that the phospho-specific antibody,pbs only possesses high specificity and an excellent signal-to-noise ratio. Black line: phospho-peptide; Rad line: non-phospho peptide
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide,40% Glycerol.
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