| Gene Symbol |
NLRC4
|
| Gene Synonyms |
CLAN IPAF AIFEC CLAN1 CLANA CLANB CLANC CLAND FCAS4 CARD12 CLR2.1 |
| Gene Full Name |
NLR family CARD domain containing 4 |
| Gene Summary |
This gene encodes a member of the caspase recruitment domain-containing NLR family. Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage and other cellular stresses. Mutations in this gene result in autoinflammation with infantile enterocolitis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014] |
| Alternative Names |
Rabbit IgG in phosphate buffered saline pH 7.4 150mM NaCl 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt. |
| Molecular Weight(MW) |
117kDa |
| Cellular Localization |
Cytoplasm, Inflammasome |