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BAD Antibody

Catalog Number：OM272168

  • Immunohistochemistry staining of BAD in cerebellum tissue using BAD Antibody.

Product Profile

Product Name BAD Antibody
Antibody Type Primary Antibodies
Product description 
Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain containing pro-apoptotic proteins, such as Bax, Bid, and Bik, form a growing subclass of the Bcl-2 family. Another such protein is the Bcl-2-antagonist of cell death (Bad). Bad regulates apoptosis by forming heterodimers with anti-apoptotic proteins Bcl-2 and Bcl-xL, thereby preventing them from binding with Bax. Bad activity is regulated by its phosphorylation; it is inactivated by kinases such as Akt and MAP kinase and thus promotes cell survival, whereas JNK-induced phosphorylation promotes the apoptotic role of Bad.
Immunogen 
BAD antibody was raised against amino acids surrounding Serine 112 of BAD (Human).

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

IHCWB
BAD antibody can be used in ELISA, Western Blot, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 10 μg/mL.:
Species Reactivity

HumanMouseRat
Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Symbol BAD
Alternative Names
BAD
BBC2
Bcl-2-like protein 8
BCL2-binding component 6
BCL2L8
BBC6
BCL-X/BCL-2 binding protein
Bcl-2-binding component 6
Bcl2 antagonist of cell death
BCL2-binding protein
Bcl2-L-8
Tissue Specificity pSer112

Database Links

Entrez Gene 572
Protein Accession Q92934

Application

  • Application

    Immunohistochemistry staining of BAD in cerebellum tissue using BAD Antibody.

Application Notes
BAD antibody can be used in ELISA, Western Blot, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 10 μg/mL.:

Additional Information

Form Liquid
Storage Instructions BAD antibody should be stored long term (months) at -80 ˚C and short term (days) at -20 ˚C. As with all antibodies avoid freeze/thaw cycles.
Storage Buffer PBS, 0.02% sodium azide, 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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  • Catalog Number: OM272168
  • Price: $336.00
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  • Lead time: 4~6 Week

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