All products Antibodies GLIS2 Antibody

GLIS2 Antibody

Catalog Number：OM279863

  • Immunohistochemistry of GLIS2 in mouse kidney tissue with GLIS2 antibody at 5 μg/ml.

  • Western blot analysis of GLIS2 in K562 cell lysate with GLIS2 antibody at 1 μg/ml.

Product Profile

Product Name GLIS2 Antibody
Antibody Type Primary Antibodies
Product description 
GLIS2, also known as neuronal Krueppel-like, is a 524 amino acid protein that belongs to the GLI C2H2-type zinc-finger protein family (1). GLIS2 can act either as a transcription repressor or as a transcription activator and may be involved in neuron differentiation (1,2). GLIS2 is expressed at high levels in kidney and at low levels in heart, lung and placenta. Mutations of GLIS2 have been suggested to be associated with development of progressive chronic kidney disease with characteristics resembling nephronophthisis (3,4).1) Vasanth S, ZeRuth G, Kang HS, et al. Identification of nuclear localization, DNA binding, and transactivating mechanisms of Kruppel-like zinc finger protein Gli-similar 2 (Glis2). J. Biol. Chem. 2011; 286:4749-59.
Immunogen 
GLIS2 antibody was raised against an 18 amino acid peptide near the center of human GLIS2. The immunogen is located within amino acids 260 - 310 of GLIS2.

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

ELISAIHC-PWB
GLIS2 antibody can be used for detection of GLIS2 by Western blot at 1 - 2 μg/ml. Antibody can also be used for immunohistochemistry starting at 5 μg/mL.:
Species Reactivity

HumanMouseRat
Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Symbol GLIS2
Alternative Names
GLIS family zinc finger 2
GLI-similar 2
neuronal krueppel-like protein
NKL
NPHP7
Molecular Weight(MW) Predicted: 58 kDa Observed: 60 kDa
Tissue Specificity GLIS2 antibody is human, mouse and rat reactive.

Database Links

Entrez Gene 84662
Protein Accession NP_115964

Application

  • Application

    Immunohistochemistry of GLIS2 in mouse kidney tissue with GLIS2 antibody at 5 μg/ml.

  • Application

    Western blot analysis of GLIS2 in K562 cell lysate with GLIS2 antibody at 1 μg/ml.

Positive Control 1) Cat. No. 1204 - K562 Cell Lysate
Application Notes
GLIS2 antibody can be used for detection of GLIS2 by Western blot at 1 - 2 μg/ml. Antibody can also be used for immunohistochemistry starting at 5 μg/mL.:

Additional Information

Form Liquid
Storage Instructions GLIS2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Storage Buffer GLIS2 antibody is supplied in PBS containing 0.02% sodium azide.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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  • Catalog Number: OM279863
  • Price: $336.00
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