All products Antibodies IKBKB Antibody

IKBKB Antibody

Catalog Number：OM281782

  • Immunohistochemistry staining of IKBKB in placenta tissue using IKBKB Antibody.

Product Profile

Product Name IKBKB Antibody
Antibody Type Primary Antibodies
Product description 
NFkB comprises a family of cellular transcription factors that are involved in the inducible expression of a variety of cellular genes that regulate the inflammatory response and control of cell death. In the cytoplasm NFkB is negatively modulated by the inhibitory proteins IkB. In turn IkB is phosphorylated by a cellular kinase complex called IKK. IKK is a heterodimer composed of two kinases: IKK-a and IKK-b that phosphorylate IkB leading to its degradation and the resulting translocation of NFkB to the nucleus. IKK kinase activity is modulated negatively by pharmaceutical agents such as aspirin and positively by various cellular components such as TNF- a, endotoxins and overexpression of cellular kinases like MEKK1. Aspirin appears to have its effect by inhibiting the binding of ATP to IKK.
Immunogen 
IKKb peptide corresponding to the highly conserved C-terminus region of the human protein conjugated to Keyhole Limpet Hemocyanin (KLH).

Key Feature

Clonality Polyclonal
Host Species Rabbit
Tested Applications

ELISAIFIHCIPWB
IKBKB antibody can be used in immunohistochemistry starting at 5 μg/mL.:
Species Reactivity

HumanMouseRat
Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Symbol IKBKB
Alternative Names
IKBKB
Ikk 2
IKK-B
IKK2
IKKbeta
NFKBIKB
I-kappa-B kinase 2
IKKB
I-kappa-B-kinase beta
Ikb kinase-beta
IKK Beta
IKK-beta

Database Links

Entrez Gene 3551
Protein Accession O14920

Application

  • Application

    Immunohistochemistry staining of IKBKB in placenta tissue using IKBKB Antibody.

Application Notes
IKBKB antibody can be used in immunohistochemistry starting at 5 μg/mL.:

Additional Information

Form Liquid
Storage Instructions Store IKBKB antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles.
Storage Buffer 0.01% sodium azide.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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  • Catalog Number: OM281782
  • Price: $336.00
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  • Store: Out of stock
  • Lead time: 4~6 Week

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