IKK beta Antibody

Product Profile

Product Name	IKK beta Antibody
Antibody Type	Primary Antibodies
Product description	Acts as part of the IKK complex in the conventional pathway of NF-κ-B activation and phosphorylates inhibitors of NF-κ-B thus leading to the dissociation of the inhibitor/NF-κ-B complex and ultimately the degradation of the inhibitor. Also phosphorylates NCOA3.1) Chen RA, et al. PLoS Pathog. 2008 Feb 8;4 (2): e22Yen CJ, et al. Cancer Res. 2008 Apr 15;68 (8): 2632-40
Immunogen	IKK-beta (Ab-199) antibody was raised against a peptide sequence around aa.197~201 (Q-K-Y-T-V) derived from Human IKK-β.

Key Feature

Clonality	Polyclonal
Host Species	Rabbit
Tested Applications	IFWB
	Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200:
Species Reactivity	HumanMouseRat
Concentration	1 mg/ml
Purification	Affinity purified

Target Information

Gene Symbol	IKBKB
Alternative Names	IKK2 IKKB IMD15 NFKBIKB IKK-beta I-kappa-B kinase 2 I-kappa-B-kinase beta IKK2 IkBKB
Molecular Weight(MW)	87 kDa
Tissue Specificity	This antibody detects endogenous level of total IKK-βprotein.

Database Links

Entrez Gene	3551
Protein Accession	NP_001547.1

Application

Application Notes	Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200:

Additional Information

Form	Liquid
Storage Instructions	Store antibody at -20˚C for up to one year.
Storage Buffer	Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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• Data sheet for OM281793