All products Antibodies IRF6 Antibody

IRF6 Antibody

Catalog Number：OM282319

  • Antibody used in WB on Human Jurkat 2.5 ug/ml.

Product Profile

Product Name IRF6 Antibody
Antibody Type Primary Antibodies
Product description 
IRF6 is a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in its gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation.The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.1) Beausoleil, S.A., (2004) Proc. Natl. Acad. Sci. U.S.A. 101 (33), 12130-12135.
Immunogen 
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human IRF6.

Key Feature

Clonality Polyclonal
Host Species Rabbit
Tested Applications

ELISAWB
IRF6 antibody can be used for detection of IRF6 by ELISA at 1:312500. IRF6 antibody can be used for detection of IRF6 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Species Reactivity

DogHumanMouseRatZebra Fish
Concentration 1 mg/ml
Purification Protein A

Target Information

Gene Symbol IRF6
Alternative Names
IRF6
LPS
OFC6
PIT
PPS
VWS
PPS1
VWS1
Molecular Weight(MW) 65 kDa, 69 kDa

Database Links

Entrez Gene 3664
Protein Accession NP_006138

Application

  • Application

    Antibody used in WB on Human Jurkat 2.5 ug/ml.

Positive Control 1) Cat. No. 1205 - Jurkat Cell Lysate
Application Notes
IRF6 antibody can be used for detection of IRF6 by ELISA at 1:312500. IRF6 antibody can be used for detection of IRF6 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:

Additional Information

Form Liquid
Storage Instructions For short periods of storage (days) store at 4˚C. For longer periods of storage, store IRF6 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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  • Catalog Number: OM282319
  • Price: $336.00
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  • Store: Out of stock
  • Lead time: 4~6 Week

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