Lmx1a acts as a transcriptional activator by binding to an A/T-rich sequence, the FLAT element, in the insulin gene promoter. It is required for development of the roof plate and, in turn, for specification of dorsal cell fates in the CNS and developing vertebrae.1) RIKEN (2005) Science 309 (5740), 1564-1566.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of mouse LMX1A.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
WB
LMX1A antibody can be used for detection of LMX1A by ELISA at 1:1562500. LMX1A antibody can be used for detection of LMX1A by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
LMX1A antibody can be used for detection of LMX1A by ELISA at 1:1562500. LMX1A antibody can be used for detection of LMX1A by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form
Liquid
Storage Instructions
For short periods of storage (days) store at 4˚C. For longer periods of storage, store LMX1A antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer
IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.
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