All products Antibodies LMX1A Antibody

LMX1A Antibody

Catalog Number：OM283589

  • Immunohistochemistry of LMX1A in human brain tissue with LMX1A antibody at 2.5 μg/mL.

  • Immunofluorescence of LMX1A in mouse brain tissue with LMX1A Antibodyat 20 μg/mL.

  • Immunofluorescence of LMX1A in human brain tissue with LMX1A antibody at 20 μg/mL.

  • Immunohistochemistry of LMX1A in mouse brain tissue with LMX1A Antibodyat 5 μg/mL.

  • Western blot analysis of LMX1A in rat brain tissue lysate with LMX1A antibody at (A) 1 and (B) 2 μg/mL.

Product Profile

Product Name LMX1A Antibody
Antibody Type Primary Antibodies
Product description 
LMX1A Antibody: The LIM homeobox transcription factor 1 (LMX1A) belongs to the LIM-homeodomain family. Members of this family are known to be important for pattern formation during development. LMX1A binds an A/T-rich sequence and functions in the nucleus as a transcriptional activator to the insulin gene promoter. In the developing embryo, LMX1A is expressed along the neuraxis and leads to the development of the roof plate of the vertebrae. While LMX1A is crucial for the differentiation of dopamine neurons, the related LMX1B appears to be important for both the development and the survival of these cells. It has been suggested that LMX1A might be a useful biomarker or risk factor in tumor aggressiveness.1) Failli V, Bachy I and Retaux S. Expression of the LIM-homeodomain gene Lmx1a (dreher) during development of the mouse nervous system. Mech. Dev. 2002; 118:225-8.
Immunogen 
Rabbit polyclonal LMX1A antibody was raised against a 16 amino acid peptide near the carboxy terminus of human LMX1A. The immunogen is located within amino acids 300 - 350 of LMX1A.

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

ELISAIFIHC-PWB
LMX1A antibody can be used for detection of LMX1A by Western blot at 1 - 2 μg/mL. Antibody can also be used for Immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.:
Species Reactivity

HumanMouseRat
Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Symbol LMX1A
Alternative Names
LMX1A Antibody: LMX1
LMX1.1
LIM homeobox transcription factor 1-alpha
Molecular Weight(MW) 42 kDa
Sequence Similarities 2) Cat. No. 10-301 - Human Brain Tissue Slide
Tissue Specificity At least two isoforms are known to exist. This antibody is predicted to not cross-react with LMX1B.

Database Links

Entrez Gene 4009
Protein Accession NP_796372

Application

  • Application

    Immunohistochemistry of LMX1A in human brain tissue with LMX1A antibody at 2.5 μg/mL.

  • Application

    Immunofluorescence of LMX1A in mouse brain tissue with LMX1A Antibodyat 20 μg/mL.

  • Application

    Immunofluorescence of LMX1A in human brain tissue with LMX1A antibody at 20 μg/mL.

  • Application

    Immunohistochemistry of LMX1A in mouse brain tissue with LMX1A Antibodyat 5 μg/mL.

  • Application

    Western blot analysis of LMX1A in rat brain tissue lysate with LMX1A antibody at (A) 1 and (B) 2 μg/mL.

Positive Control 1) Cat. No. 1463 - Rat Brain Tissue Lysate
Application Notes
LMX1A antibody can be used for detection of LMX1A by Western blot at 1 - 2 μg/mL. Antibody can also be used for Immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.:

Additional Information

Form Liquid
Storage Instructions LMX1A antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer LMX1A Antibody is supplied in PBS containing 0.02% sodium azide.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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  • Catalog Number: OM283589
  • Price: $336.00
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