Application
PNPLA2 Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the PNPLA2 antibody detected the PNPLA2 protein (arrow).| Product Name | PNPLA2 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PNPLA2;ATGL; Patatin-like phospholipase domain-containing protein 2; Patatin-like phospholipase domain-containing protein 2; Adipose triglyceride lipase; Patatin-like phospholipase domain-containing protein 2; Calcium-independent phospholipase A2; Patatin- |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ATGL |
|---|---|
| Alternative Names | PNPLA2 ATGL Patatin-like phospholipase domain-containing protein 2 Patatin-like phospholipase domain-containing protein 2 Adipose triglyceride lipase Patatin-like phospholipase domain-containing protein 2 Calcium-independent phospholipase A2 Patatin- |
| Molecular Weight(MW) | 55316 Da |
| Function | Catalyzes the initial step in triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets. Also has acylglycerol transacylase activity. May act coordinately with LIPE/HLS within the lipolytic cascade. Regulates adiposome size and may be involved in the degradation of adiposomes. May play an important role in energy homeostasis. May play a role in the response of the organism to starvation, enhancing hydrolysis of triglycerides and providing free fatty acids to other tissues to be oxidized in situations of energy depletion |
| Tissue Specificity | Highest expression in adipose tissue. Also detected in heart, skeletal muscle, and portions of the gastrointestinal tract. Detected in normal retina and retinoblastoma cells. Detected in retinal pigment epithelium and, at lower intensity, in the inner segments of photoreceptors and in the ganglion cell layer of the neural retina (at protein level) |
| Cellular Localization | Lipid droplet. Cell membrane; Single-pass type II membrane protein |
| Entrez Gene | 57104 |
|---|
Application
PNPLA2 Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the PNPLA2 antibody detected the PNPLA2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
