Application
SERPINA1 Antibody (Cat. #AM2047b) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the SERPINA1 antibody detected the SERPINA1 protein (arrow).| Product Name | SERPINA1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SERPINA1; AAT; PI; Alpha-1-antitrypsin; Alpha-1 protease inhibitor; Alpha-1-antiproteinase; Serpin A1; Short peptide from AAT |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 494CT5.1.1 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:1:100~1000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | AAT PI |
|---|---|
| Alternative Names | SERPINA1 AAT PI Alpha-1-antitrypsin Alpha-1 protease inhibitor Alpha-1-antiproteinase Serpin A1 Short peptide from AAT |
| Molecular Weight(MW) | 46737 Da |
| Function | Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin |
| Tissue Specificity | Plasma. |
| Cellular Localization | Secreted. |
| Entrez Gene | 5265 |
|---|---|
| Nucleotide Accession | NP_000286.3 |
Application
SERPINA1 Antibody (Cat. #AM2047b) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the SERPINA1 antibody detected the SERPINA1 protein (arrow).| Application Notes | WB:1:100~1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
