Application
Western blot analysis of SPPL3(arrow) using rabbit polyclonal SPPL3 Antibody (N-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the SPPL3 gene (Lane 2) (Origene Technologies).| Product Name | SPPL3 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SPPL3; IMP2; PSL4; Signal peptide peptidase-like 3; Intramembrane protease 2; Presenilin homologous protein 1; Presenilin-like protein 4 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | IMP2 PSL4 |
|---|---|
| Alternative Names | SPPL3 IMP2 PSL4 Signal peptide peptidase-like 3 Intramembrane protease 2 Presenilin homologous protein 1 Presenilin-like protein 4 |
| Molecular Weight(MW) | 42563 Da |
| Function | Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane |
| Tissue Specificity | Ubiquitous. |
| Cellular Localization | Membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein Note=Restricted to the early secretory compartment |
| Entrez Gene | 121665 |
|---|
Application
Western blot analysis of SPPL3(arrow) using rabbit polyclonal SPPL3 Antibody (N-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the SPPL3 gene (Lane 2) (Origene Technologies).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
