Application
IGF2BP2 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the IGF2BP2 antibody detected the IGF2BP2 protein (arrow).Application
IGF2BP2 antibody(C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human spleen tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the IGF2BP2 antibody(C-term) for immunohistochemistry. Clinical relevance has not been evaluated.Application
IGF2BP2 Antibody (C-term) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | IGF2BP2 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | IGF2BP2; IMP2; VICKZ2; Insulin-like growth factor 2 mRNA-binding protein 2; Hepatocellular carcinoma autoantigen p62; IGF-II mRNA-binding protein 2; VICKZ family member 2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | IMP2 VICKZ2 |
|---|---|
| Alternative Names | IGF2BP2 IMP2 VICKZ2 Insulin-like growth factor 2 mRNA-binding protein 2 Hepatocellular carcinoma autoantigen p62 IGF-II mRNA-binding protein 2 VICKZ family member 2 |
| Molecular Weight(MW) | 66121 Da |
| Function | Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. Binding is isoform-specific. May regulate translation of target mRNAs |
| Tissue Specificity | Expressed in oocytes, granulosa cells of small and growing follicles, Leydig cells, spermatogonia and semen (at protein level). Expressed in testicular cancer (at protein level) Expressed weakly in heart, placenta, skeletal muscle, bone marrow, colon, kidney, salivary glands, testis and pancreas. Detected in fetal liver, fetal ovary, gonocytes and interstitial cells of the testis |
| Cellular Localization | Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Localizes at the connecting piece and the tail of the spermatozoa |
| Entrez Gene | 10644 |
|---|---|
| Nucleotide Accession | NP_001007226.1 NP_006539.3 |
Application
IGF2BP2 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the IGF2BP2 antibody detected the IGF2BP2 protein (arrow).
Application
IGF2BP2 antibody(C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human spleen tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the IGF2BP2 antibody(C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
IGF2BP2 Antibody (C-term) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
