Application
Figure 1: Western blot analysis using anti-AAT mAb against human plasma (1) and NIH/3T3 cell lysate (2).| Product Name | AAT Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PI; A1A; AAT; PI1; A1AT; SERPINA1 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 2B12 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:1:500 - 2000. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | AAT PI |
|---|---|
| Alternative Names | PI A1A AAT PI1 A1AT SERPINA1 |
| Molecular Weight(MW) | 46737 Da |
| Function | Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin |
| Tissue Specificity | Plasma. |
| Cellular Localization | Secreted. |
| Entrez Gene | 5265 |
|---|---|
| Nucleotide Accession | NP_001121179.1 |
Application
Figure 1: Western blot analysis using anti-AAT mAb against human plasma (1) and NIH/3T3 cell lysate (2).| Application Notes | WB:1:500 - 2000. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified recombinant fragment of human AAT expressed in E. Coli. |
