Rabbit polyclonal to APE1Apurinic / Apyrimidinic Endonuclease (APE 1 or REF 1) is responsible for the incision of DNA at abasicsites during base excision repair. It has also been shown to stimulate the sequence-specific DNA binding activity of Fos-Jun (AP 1) heterodimers. Alterations in APE 1 levels have been described insome cancers.
Immunogen
Full length human APE1 purified from E. coli
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
For WB: Use at a dilution of 1:2,500. Predicted molecular weight: 38 kDa. Optimal dilutions/concentrations should be determined by the researcher.