Application
Immunohistochemical staining of ARTS in human lung tissue with ARTS antibody at 2μg/ml.Application
Western blot analysis of ARTS expression in human lung (lane 1),spleen (lane 2), and kidney (lane 3) tissue lysates with ARTS antibody at 2μg /ml.| Product Name | ARTS antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to ARTSApoptosis is related to many diseases and development. Mitochondrial proteins, such as cytochrome c, Apaf-1, and AIF play important role in apoptosis. A novel mitochondrial septin-like protein was identified recently and designated ARTS for apoptosis related protein in TGF-b signaling pathway (1). ARTS that is encoded by the human septin H5/PNUTL2/CDCrel2b gene (1-4) is located to mitochondria and translocates to the nucleus when apoptosis occurs. ARTS is expressed in many tissues. It enhances cell death induced by TGF-b and, to a lesser extent, by other apoptotic agents, such as TNF-a and Fas ligand. |
| Immunogen | Synthetic peptide: KRFLEDTTDDGE, corresponding to amino acids 3-14 of Human ARTS. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| Western blot at 0.5 to 2 μg/ml. Human lung, kidney and spleen tissue lysates can be used as a positive control and a band at 32 kDa can be detected.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | hCDCREL2 603696 hCDCREL-2 H5 hucep-7 5414 ARTS O43236 hucep7 SEPT4 PNUTL2 CE5B3 hucep 7 hCDCREL 2 |
|---|---|
| Target | ARTS |
| Cellular Localization | Mitochondrial and Nuclear |
Application
Immunohistochemical staining of ARTS in human lung tissue with ARTS antibody at 2μg/ml.
Application
Western blot analysis of ARTS expression in human lung (lane 1),spleen (lane 2), and kidney (lane 3) tissue lysates with ARTS antibody at 2μg /ml.| Positive Control | Human lung, kidney and spleen tissue lysates. |
|---|---|
| Application Notes | Western blot at 0.5 to 2 μg/ml. Human lung, kidney and spleen tissue lysates can be used as a positive control and a band at 32 kDa can be detected.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Upon receipt - Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide |
