Application
Western blot analysis of ATM (pSer1981). Lane 1: MW Lane 2: HeLa Lane 3: γ-irradiated HeLa| Product Name | ATM (phospho Ser1981) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to ATM (phospho Ser1981)The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. [provided by RefSeq, Aug 2010] |
| Immunogen | Synthetic phospho-peptide corresponding to amino acids surrounding Ser1981 or human ATM |
| Modification | p-Ser1981 |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB: Use at a concentration of 1 μg/ml (ECL). Optimal dilutions/concentrations should be determined by the researcher: |
|
| Species Reactivity | Human |
| Concentration | 0.5mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | Phospho ATM (pS1981) phospho S1981 ATM ATD ATM (Phospho Ser1981) phospho ATM Ser1981 ATM phospho ATM (Phospho S1981) TELO1 ATM phospho S1981 ATA ATM S1981 phospho ATM Ser1981 phospho AT1 ATM (pS1981) ATC ATM pho |
|---|---|
| Target | ATM (phospho Ser1981) |
Application
Western blot analysis of ATM (pSer1981). Lane 1: MW Lane 2: HeLa Lane 3: γ-irradiated HeLa| Positive Control | Irradiated HeLa cell lysates |
|---|---|
| Application Notes | For WB: Use at a concentration of 1 μg/ml (ECL). Optimal dilutions/concentrations should be determined by the researcher: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Phosphate-buffered saline, pH7.2 containing 0.09% sodium azide |
