Application
IHC-P analysis of human gastric carcinoma using ATM (phospho Ser1981) antibody [EP1890Y] at a dilution of 1:100.Application
WB analysis of lysates from (1) untreated and (2) doxorubicin-treated HEK293 cells (10 μg per lane) using ATM (phospho Ser1981) antibody [EP1890Y] at a dilution of 1:10,000.Application
IHC analysis of endometrial carcinoma tissue using ATM (phospho Ser1981) antibody [EP1890Y].| Product Name | ATM (phospho Ser1981) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit monoclonal antibody [EP1890Y] to ATM (phospho Ser1981)The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. [provided by RefSeq, Aug 2010] |
| Immunogen | A synthetic peptide corresponding to residues surrounding serine 1981 of human ATM was used as an immunogen. |
| Modification | p-Ser1981 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Clone Number | EP1890Y |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHCIHC-PIPWB |
| ICC/IF:1:200~1:500 IHC:1:50~1:200 IHC-P:1:50~1:200 IP:1:100~1:500 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | Phospho ATM (pS1981) ATD ATM (Phospho Ser1981) Phospho ATM ATM S1981 Phospho ATM (Phospho S1981) ATM Phospho Ser1981 TELO1 ATA AT1 ATM (pS1981) A |
|---|---|
| Target | ATM (phospho Ser1981) |
Application
IHC-P analysis of human gastric carcinoma using ATM (phospho Ser1981) antibody [EP1890Y] at a dilution of 1:100.
Application
WB analysis of lysates from (1) untreated and (2) doxorubicin-treated HEK293 cells (10 μg per lane) using ATM (phospho Ser1981) antibody [EP1890Y] at a dilution of 1:10,000.
Application
IHC analysis of endometrial carcinoma tissue using ATM (phospho Ser1981) antibody [EP1890Y].| Application Notes | ICC/IF:1:200~1:500 IHC:1:50~1:200 IHC-P:1:50~1:200 IP:1:100~1:500 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
| Storage Buffer | PBS containing 50% Glycerol, 0.05% BSA and 0.01% Sodium azide. |
