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BCL10 antibody

Catalog Number:OM241153
OM241153
Discount Price
OM241153-100ul
1~2 Week
100ul
OM241153-50ul
50ul
1~2 Week
Product Profile
Product Name BCL10 antibody
Antibody Type Primary Antibodies
Product description Mouse monoclonal antibody [4A8] to BCL10Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1.
Immunogen Full length human recombinant protein of human BCL10 (NP_003912) produced in HEK293T cell.
Key Feature
Clonality Monoclonal
Isotype IgG1
Clone Number 4A8
Host Species Mouse
Tested Applications FACSICC/IFIHCIHC-PWB
IHC 1:50 :
Species Reactivity Human
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Synonyms CARMEN
mE10
cE10
BCL10
CLAP
CIPER
c-E10
c E10
Target BCL10
Tissue Specificity is specific for human BCL10 (NP_003912).
Cellular Localization Appears to have a perinuclear, compact and filamentous pattern of expression. Also found in the nucleus of several types of tumor cells. Colocalized with DPP4 in membrane rafts.
Application

Application

Flow cytometric Analysis of Jurkat cells, using anti-BCL10 antibody,(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).

Application

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-BCL10 mouse monoclonal antibody. ( Dilution 1:50)

Application

Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-BCL10 mouse monoclonal antibody. ( Dilution 1:50)

Application

Anti-BCL10 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected with BCL10

Application

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BCL10 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BCL10 .

Application

Immunohistochemical staining of paraffin-embedded Human liver tissue using anti-BCL10 mouse monoclonal antibody. ( Dilution 1:50)
Application Notes IHC 1:50 :
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4°C or aliquot into working amounts and store at -20°C. For long-term storage, store at -70°C (aliquotted). Avoid repeated freeze-thaw cycles.
Storage Buffer PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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