Application
Surface staining of human peripheral blood cells with anti-CD300a (MEM-260) PE.| Product Name | CD300a antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse Monoclonal antibody [MEM-260] to CD300aCD300a (CMRF-35H, IRp60) is a non-MHC-specific inhibitory receptor of immunoglobulin superfamily, which contains three immunoreceptor tyrosine-based inhibitory motifs (ITIMs) that associate with SH2-containing phosphatases SHP-1 and SHP-2. CD300a is expressed on many cell types including T cells, NK cells, neutrophils, eosinophils or mast cells. Its triggering inhibits activating signals such as those of IL5, GM-CSF or eotaxin, as well as supresses mast cell degranulation or NK cell cytotoxic activity.Entrez Gene: 17q25.1 |
| Immunogen | HPB human acute lymphoid leukemia cell line |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | MEM-260 |
| Host Species | Mouse |
| Tested Applications | FACSWB |
|
FACS: 2 μg/ml. : |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CMRF-35-H9 CMRF-35H CMRF35H CMRF35H9 IGSF12 IRC1 IRC2 IRp60 |
|---|---|
| Target | CD300a |
| Tissue Specificity | The antibody MEM-260 reacts with CD300a, a 60 kDa leukocyte transmembrane glycoprotein expressed on human granulocytes, monocytes, neutrophils, NK cells, mast cells and dendritic cells, 25% of circulating T cells and 15% of circulating B cells. |
Application
Surface staining of human peripheral blood cells with anti-CD300a (MEM-260) PE.| Positive Control | HPB cell line |
|---|---|
| Application Notes |
FACS: 2 μg/ml. : |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 2-8°C. Do not use after expiration date stamped on vial label. For long-term storage aliquot and store at -20°C. Avoid freeze/thaw cycles. |
| Storage Buffer | PBS (pH7.4) and 15 mM sodium azide as a preservatives. |
