| Product Name | Clusterin antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [Hs-3] to ClusterinApolipoprotein J is the major secreted product of Sertoli cells and is thought to play a critical role in spermatogenesis. The protein was shown to be a normal constituent of human blood, and is also thought to be a control mechanism of the complement cascade. It prevents the binding of a C5b-C7 complex to the membrane of the target cell and in this way inhibits complement-mediated cytolysis. |
| Immunogen | Freshly ejaculated human sperms were washed in PBS and extracted in 3% acetic acid, 10% glycerol, 30 mM benzaminidine. The acid extract was dialyzed against 0.2% acetic acid and subsequently used for immunization. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | Hs-3 |
| Host Species | Mouse |
| Tested Applications | ICC/IFIHC |
| IF: Use at an assay dependent dilution. IHC: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Protein A |
| Gene Synonyms | SP-40 SP40 MGC24903 APOJ CLI 185430 SGP-2 TRPM-2 Apo J AAG4 CLU TRPM2 P10909 KUB1 1191 SGP2 SP 40 SGP 2 TRPM 2 |
|---|---|
| Target | Clusterin |
| Application Notes | IF: Use at an assay dependent dilution. IHC: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage add 50% glycerol, aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 |
