Application
WB analysis of HepG2 lysate using Cytochrome P450 3A5 antibody [F18 P3 B6].| Product Name | Cytochrome P450 3A5 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [F18 P3 B6] to Cytochrome P450 3A5This gene,CYP3A5, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. The enzyme metabolizes drugs such as nifedipine and cyclosporine as well as the steroid hormones testosterone, progesterone and androstenedione. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. This cluster includes a pseudogene, CYP3A5P1, which is very similar to CYP3A5. This similarity has caused some difficulty in determining whether cloned sequences represent the gene or the pseudogene. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jun 2010] |
| Immunogen | Synthetic peptide corresponding to residues E S R D G T L S G E, conjugated to ovalbumin. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | F18 P3 B6 |
| Host Species | Mouse |
| Tested Applications | ELISAIHCIHC-PWB |
| IHC-P: 1-5 µg/ml: |
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| Species Reactivity | HumanBovine |
| Concentration | 1mg/ml |
| Gene Synonyms | CP35 cytochrome P450 family 3 subfamily A polypeptide 5 CYP3A5 CYPIIIA5 PCN3 P450PCN3 |
|---|---|
| Target | Cytochrome P450 3A5 |
Application
WB analysis of HepG2 lysate using Cytochrome P450 3A5 antibody [F18 P3 B6].| Application Notes | IHC-P: 1-5 µg/ml: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | -20° C, Avoid Freeze/Thaw Cycles |
| Storage Buffer | Ascites containing 0.05 % sodium azide |
