Mouse polyclonal antiserum to human DNA polymerase deltaDNA polymerase d (delta) functions in DNA replication and DNA repair. It also possesses 3' to 5' exonuclease activity. In leading strand synthesis it requires the processivity factor, PCNA. It is also possibly involved in the completion of DNA synthesis during Okazaki fragment elongation following the initiation of synthesis by the DNA polymerase a/primase complex
Immunogen
Recombinant protein encoding amino acids 1-140 of the large subunit of human DNA polymerase d.
Key Feature
Clonality
Monoclonal
Isotype
IgG
Host Species
Mouse
Tested Applications
WB
For WB: Use at a dilution of 1:500. Optimal dilutions/concentrations should be determined by the researcher.:
Species Reactivity
Human
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
P28340 DNA polymerase delta 174761 5424 POLD1 POLD
Target
DNA polymerase delta
Application
Application
Detection of human polymerase delta protein in Jurkat whole cell lysate using GeneTex DNA polymerase delta polyclonal antiserum
Positive Control
HeLa
Application Notes
For WB: Use at a dilution of 1:500. Optimal dilutions/concentrations should be determined by the researcher.:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.