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ERAB antibody

Catalog Number:OM251859
OM251859
Discount Price
OM251859-100ul
1~2 Week
100ul
OM251859-50ul
50ul
1~2 Week
Product Profile
Product Name ERAB antibody
Antibody Type Primary Antibodies
Product description Mouse monoclonal antibody [11A2] to ERABFunctions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/RG9MTD1, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD).
Immunogen Full length human recombinant protein of human ERAB (NP_004484) produced in HEK293T cell.
Key Feature
Clonality Monoclonal
Isotype IgG1
Clone Number 11A2
Host Species Mouse
Tested Applications FACSICC/IFIHCIHC-PWB
IHC 1:50 :
Species Reactivity Human
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Synonyms ABAD
17bHSD10
17b-HSD10
MHBD
HSD17B10
ERAB
17b HSD10
Target ERAB
Tissue Specificity is specific for human ERAB (NP_004484).
Application

Application

Flow cytometric Analysis of Hela cells, using anti-HSD17B10 antibody,(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).

Application

Immunohistochemical staining of paraffin-embedded Human breast tissue using anti-HSD17B10 mouse monoclonal antibody.

Application

Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-HSD17B10 mouse monoclonal antibody.

Application

Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-HSD17B10 mouse monoclonal antibody.

Application

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HSD17B10 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HSD17B10.

Application

Immunofluorescent staining of HepG2 cells using anti-HSD17B10 mouse monoclonal antibody .

Application

Immunohistochemical staining of paraffin-embedded Human endometrium tissue using anti-HSD17B10 mouse monoclonal antibody.

Application

Anti-HSD17B10 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected with HSD17B10

Application

Flow cytometric Analysis of Jurkat cells, using anti-HSD17B10 antibody,(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).
Application Notes IHC 1:50 :
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4°C or aliquot into working amounts and store at -20°C. For long-term storage, store at -70°C (aliquotted). Avoid repeated freeze-thaw cycles.
Storage Buffer PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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