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ERAB antibody

Catalog Number:OM251860
OM251860
Discount Price
OM251860-100ul
1~2 Week
100ul
OM251860-50ul
50ul
1~2 Week
Product Profile
Product Name ERAB antibody
Antibody Type Primary Antibodies
Product description Mouse monoclonal antibody [3B5] to ERABFunctions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/RG9MTD1, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD).
Immunogen Protein expressed in 293T cell transfected with human ERAB expression vector
Key Feature
Clonality Monoclonal
Isotype IgG1
Clone Number 3B5
Host Species Mouse
Tested Applications IHC-PWB
IHC 1:50 :
Species Reactivity Human
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Synonyms ABAD
17bHSD10
17b-HSD10
MHBD
HSD17B10
ERAB
17b HSD10
Target ERAB
Tissue Specificity is specific for human ERAB.
Application

Application

Immunohistochemical staining of paraffin-embedded liver tissue using anti-HSD17B10 mouse monoclonal antibody. ( Dilution 1:50)

Application

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HSD17B10 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HSD17B10 .
Application Notes IHC 1:50 :
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4°C or aliquot into working amounts and store at -20°C. For long-term storage, store at -70°C (aliquotted). Avoid repeated freeze-thaw cycles.
Storage Buffer PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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